AGROCHEMICALS & CHEMICALS
At Medbotics LLP, we are a leading force in advancing agrochemical research and development. Driven by a deep commitment to agricultural innovation, Medbotics LLP offers a comprehensive suite of services to ensure the safety and effectiveness of your agrochemical products. Our Expertise includes: Genetic Toxicology Studies, In Vitro Studies , Acute Studies, Repeated Dose, Developmental and Reproductive Toxicology Studies, Endocrine Disruption Studies, Neurotoxicity Studies, Chronic & Carcinogenicity Studies, Metabolism Studies-Using 14C labeled compounds, Ecotoxicology (Ecotox) studies , Analytical Chemistry Services, Physical Chemical Properties, 5 Batch Analysis, Residue, Environment Fate and Behavior Studies, Environmental Risk Assessment.
AGROCHEMICALS, PESTICIDES, INSECTICIDES AND BIOCONTROL ANALYSIS
Your Partner in Bringing Safe and Effective Agrochemicals to Market
At Medbotics LLP, we understand the critical role of comprehensive testing in the development and commercialization of agrochemicals. Our team of expert scientists and consultants offers a complete suite of services to empower your success:
Extensive Expertise
Support for the Agrochemical, Pesticides, Insecticides and Biocontrol sectors.
Proven track record of helping companies bring products to market quickly and cost-effectively.
Streamlined Testing Services
Leverage our network of reputable CROs (Contract Research Organizations) for efficient study placement and management.
Comprehensive Agrochemical Testing
- Acute 6-pack Studies
- Genotoxicity Studies
- Ecotoxicology Studies
- Acute, Repeat Dose & Chronic Toxicology Studies
- Analytical Chemistry Studies
- Physicochemical Studies
- Environmental Fate and Metabolism (Water, Soil and Air)
- Residual Studies (Crops, Fruits and Vegetables)
- 5- Batch Analysis
- Shelf-life and Chemistry Studies
- Agrochemicals Impurities Profiling
- Safety & Efficacy: Acute, repeat dose, and chronic toxicology studies.
- Quality & Purity: Analytical and physicochemical characterization.
- Environmental Impact: Ecotoxicology and environmental fate & metabolism studies.
- Regulatory Compliance: Residual studies, shelf-life testing, and regulatory guidance.
Services for Biocontrol Products
- Regulatory strategy for Bio Stimulants and Biofertilizer – Guidelines for product testing & its registration in India
- Scientific advice and Expert opinion for new biological product introduction & its registration in India
- Dossier data generation with SAU (State Agricultural Universities) & OECD GLP certified labs for product registrations of Bio Stimulant and Biofertilizer
Services on New Plant-derived molecules (Plants Derived Metabolites)
- Guidance for the selection of new-generation biological molecules i.e plant metabolites for the control of insect pests & diseases
- Dossier data (from OECD GLP-certified labs) generation for plant metabolites
Services on Biotech Crops (Transgenic crops)
- Transgenic crops dossier data generation, procedures for applying to RCGM/GEAC for protocol approvals
- Practical guidance for conducting Event Selection Trials & BRL -1 & BRL-2 trials for transgenic crops
Services on Access to Plant Genetic Resources & Regulatory Approval
Guidance for obtaining approval from NBA for germplasm sourcing/exchanging, access to bio-materials
Services on Plant Variety Protection & Phytosanitary requirements
- PPV & FRA registration for crops
- Phytosanitary certificate requirements for importing/exporting germplasm
Additional Services
- Technology acquisition & transfer
- Plant genetic resources access & regulatory approval
- Plant protection & phytosanitary requirements
Benefits of Partnering with Medbotics LLP
- Faster Time to Market: Our efficient processes ensure rapid project completion with high-quality data.
- Cost-Effectiveness: We optimize testing strategies to deliver solutions that fit your budget.
- Regulatory Expertise: Gain valuable guidance on navigating complex regulations and securing approvals.
- Comprehensive Support: We act as your single point of contact for all testing and registration needs.
REACH STUDIES FOR INDUSTRIAL CHEMICALS
Understanding REACH: Safeguarding Human Health and the Environment REACH, the Registration, Evaluation, Authorization and Restriction of Chemicals regulation, is a cornerstone of the European Union’s commitment to chemical safety. Implemented in early 2007, REACH aims to protect human health and the environment from the risks associated with chemicals.
Centralized Management by ECHA
The European Chemicals Agency (ECHA) plays a vital role in facilitating compliance and promoting the safe use of chemicals across the EU. ECHA maintains a central database accessible to authorities and the public, containing information on registered substances.
Manufacturer and Importer Responsibilities
Companies that manufacture, import, or use chemicals within the EU have specific responsibilities under REACH. This includes submitting data on the hazardous properties of their substances, following a globally harmonized classification and labeling system. Crucially, companies must provide detailed toxicological data and classification information.
Benefits of REACH
REACH fosters a transparent and accountable system for chemical management within the EU. By requiring comprehensive data on chemical properties and potential risks, REACH empowers informed decision-making to ensure the safety of citizens and the environment.
GENETIC TOXICOLOGY STUDIES
- Bacterial Reverse Mutation Test (Ames Test) (OECD 471)
- In Vitro Mammalian Chromosomal Aberration Test (CHO cells) (OECD 473)
- In Vitro Mammalian Chromosomal Aberration Test (Human Peripheral Blood Lymphocytes-HPBL) (OECD 473)
- In Vitro Mammalian Cell Gene Mutation Test Using the HPRT and XPRT genes (OECD 476)
- In Vitro Mammalian Cell Micronucleus Test (Human Peripheral Blood Lymphocytes-HPBL) (OECD 487)
- In Vitro Mammalian Cell Gene Mutation Test Using the Thymidine Kinase Gene (OECD 490)
- Mammalian Erythrocyte Micronucleus Test (OECD 474)
- Mammalian Bone Marrow Chromosomal Aberration Test (OECD 475)
IN VITRO STUDIES
- EpiSkin-In Vitro Skin Corrosion (OECD 431)
- EpiSkin-In Vitro Skin Irritation (OECD 439)
- In Vitro Eye Irritation [Bovine Corneal Opacity and Permeability (BCOP) Test] (OECD 437)
- In Vitro Eye Irritation EpiOcular (OECD 492)
- In Vitro Skin Sensitization [Dermal Peptide Reactivity Assay (DPRA)] (OECD 442C)
- In Vitro Skin Sensitization- ARE-Nrf2 Luciferase Test Method [KeratinoSens] (OECD 442D)
- In Vitro Skin Sensitization [Human Cell Line (U937-U-SENS) Activation Test (h-CLAT)] (OECD 442E)
- In Vitro Skin Absorption: Franz Cell Diffusion Assay (OECD 428)
- In vitro Cytotoxicity in Balb/c 3T3 LD50 (OECD 129)
ACUTE STUDIES
- Acute Oral Toxicity Study in Rats (OECD 420/423/425)
- Acute Dermal Toxicity Study in Rats (OECD 402)
- Acute Inhalation Study in Rats (OECD 403)
- Acute Dermal Irritation/Corrosion Study in Rabbits (OECD 404)
- Acute Eye Irritation/Corrosion Study in Rabbits (OECD 405)
- Skin Sensitization Study in Guinea Pigs (OECD 406)
- Local Lymph Node Assay (LLNA) in CBA/Ca mice (OECD 429)
REPEATED DOSE
- Dose range finding (7 to 14 day) toxicology studies in Mice/Rats
- Dose range finding (7 to 14 day) toxicology studies in Beagle Dogs
- 28-day repeat dose toxicity studies in Mice/Rats
- 28-day repeat dose toxicity studies in Beagle Dogs
- 90-day repeat dose toxicity studies in Mice/Rats
- 90-day repeat dose toxicity studies in Beagle Dogs
- 21/28-day repeat dose dermal toxicity studies in Rats/Rabbits
- 90-day repeat dose dermal toxicity studies in Rats/Rabbits
- 28-day Inhalation toxicity studies in Rats
- 90-day Inhalation toxicity studies in Rats
DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY STUDIES
- Prenatal Developmental Toxicity Study in Mice/rats/Rabbits (OECD 414)
- One Generation Reproductive Toxicity Study in Mice/Rats (OECD 415)
- Two Generation Reproductive Toxicity Study in Mice/Rats (OECD 416)
- Reproduction/Developmental Toxicity Screening Test in Rats (OECD 421)
- Combined Repeated Dose with Reproduction/Developmental Toxicity Screening Test in Rats (OECD 422)
- Extended One-Generation Reproduction Toxicity Study in Rats (OECD 443)
ENDOCRINE DISRUPTION STUDIES
- Uterotrophic Bioassay in Rats (OECD 440)
- Hershberger Bioassay in Rats (OECD 441)
NEUROTOXICITY STUDIES
- Delayed Neurotoxicity of Organophosphorus substances following acute exposure (OECD 418)
- Delayed Neurotoxicity of Organophosphorus substances 28-day repeated dose study (OECD 419)
- Neurotoxicity Study in Rats (OECD 424)
- Developmental Neurotoxicity Study in Rats (OECD 426)
CHRONIC & CARCINOGENICITY STUDIES
- Carcinogenicity study in Mice/Rats (OECD 451)
- Chronic Toxicity studies in Mice/Rats (OECD 452)
- Combined Chronic Toxicity/Carcinogenicity study in Mice/Rats (OECD 453)
METABOLISM STUDIES-USING 14C LABELED COMPOUNDS
- Toxicokinetics / Mass balance study in rats (OECD 417)
- Skin absorption study in rats (OECD 427)
- Metabolism in Livestock -Goat, Chicken and Swine (OECD 503)
- Residues in Livestock -Goat, Chicken and Swine (OECD 505)
ECOTOXICOLOGY (ECOTOX) STUDIES
- Acute toxicity test in fish
- Acute toxicity test in daphnia
- Acute toxicity test in alga
- Acute toxicity test in earthworm
- Acute toxicity test in honey bee (oral & contact)
- Ready biodegradability study (carbon dioxide evolution test)
- Acute Oral Toxicity Study in birds [Japanese Quails/Chicken/Pigeon] (OECD 223)
- Avian Dietary Toxicity Study in Japanese Quails (OECD 205)
- Reproductive Toxicity in Birds-Japanese Quails (OECD 206)
RESIDUE, ENVIRONMENT FATE AND BEHAVIOR STUDIES
- Environmental Risk Assessment
- Ecotoxicology Studies
Services we have for AGROCHEMICALS & CHEMICALS
Our Motto
Our ‘Client First’ motto drives us to prioritise regulatory challenges which allow both flexibility for the client and compliance to be a reference of excellence in the global supply of solutions for validation in order to enable regulatory compliance for companies of all sizes.
Vision
Following the best regulatory practices combining our expertise & experience with client’s insights
Mission
To deliver tangible and sustainable results to the clients by innovative proposals, digital transformation, information security and sustainability.
Medbotics LLP