FOOD & NUTRACEUTICALS

Driven by a growing public demand for ethical practices and stricter regulations like the EU Cosmetics Directive (76/768/EEC), the development of alternative toxicological methods is accelerating. Vanta Bioscience recognizes the importance of the 3Rs (Replacement, Reduction, and Refinement) in animal testing. We are committed to offering validated alternative methods that deliver reliable results while minimizing animal use.

  • Safety Evaluation: Addressing Potential Risks: To ensure consumer safety, direct food additives and color additives undergo a thorough evaluation process. This assessment assigns a “Concern Level” (low, intermediate, or high) based on two key factors:
  • Toxicological Potential: This considers the inherent toxicity of the additive, predicted from its chemical structure (low, intermediate, or high).
  • Cumulative Human Exposure: This estimates the amount of the additive a person might consume over time. By combining these factors, the evaluation aims to identify any potential safety concerns associated with the use of the additive in food.

Services offered by Medbotics LLP Consulting Group

Mutagenicity & In-vivo Toxicology Services for GRAS & Food Additives

MUTAGENICITY STUDIES

  • Test for gene mutations in bacteria (Ames test)
  • In vitro test with cytogenetic evaluation of chromosomal damage using mammalian cells
  • In vitro mouse lymphoma thymidine kinase+/- gene mutation assay
  • In vivo test for chromosomal damage using mammalian hematopoietic cells
MUTAGENICITY STUDIES
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IN-VIVO TOXICOLOGY

  • Short term toxicity with rodents (28 days)
  • Sub-chronic toxicity studies with rodents (90 days)
  • Chronic toxicity studies with rodents (1 year)
  • Carcinogenicity
  • Two-Generation Reproduction and Teratology Study
IN-VIVO TOXICOLOGY
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Services we have for FOOD & NUTRACEUTICALS

MUTAGENICITY STUDIES
IN-VIVO TOXICOLOGY
medbotics llp

Our Motto

Our ‘Client First’ motto drives us to prioritise regulatory challenges which allow both flexibility for the client and compliance to be a reference of excellence in the global supply of solutions for validation in order to enable regulatory compliance for companies of all sizes.

Vision

Following the best regulatory practices combining our expertise & experience with client’s insights

Mission

To deliver tangible and sustainable results to the clients by innovative proposals, digital transformation, information security and sustainability.

Medbotics LLP

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